AICF's 2020-21 Fellow:
Elisa Bergaggio, PhD
Generation of ALK CAR-T Cells for Neuroblastoma Therapy
"I obtained my PhD in Molecular Medicine in 2019 at University of Torino when, for the last months of the PhD, I joined the laboratory of Dr. Roberto Chiarle at Boston Children’s Hospital. In the Chiarle’s lab, I’m currently doing my post-doc to find new therapies for neuroblastoma, the most deadly cancer in children. In particular, my research is focused on the generation of ALK chimeric antigen receptor (CAR)-T cells to specifically target the ALK protein expressed on the surface of neuroblastoma cells. This strategy can eventually be associated with other drugs, including ALK inhibitors, to improve patient’s outcome."